2,9-Dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives and pharma

Details 2,9-Dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives and pharma 2,9-Dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives and pharma

1978-05-11

1980-06-10

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

2603403, C07D31908, A61K 31335

Patent

active

042073316

ABSTRACT:
New 2,9-dioxatricyclo[4,3,1,0.sup.3,7 ] decane derivatives are disclosed which are substituted by an amino methyl group in the C.sub.3 position, and which exhibit sedative, especially sleep improving properties, and which have the formula ##STR1## wherein R.sub.1 represents an amino group one of R.sub.2 and R.sub.3 is hydrogen and the other represents hydroxy acyloxy or carbamyloxy or R.sub.2 and R.sub.3 jointly represent oxygen one of R.sub.4 and R.sub.5 is hydrogen and the other represents alkyloxy or aralkyloxy y and y' each represent hydrogen or jointly form a bond and their pharmacologically acceptable salts, as well as pharmaceutical formulations thereof.

REFERENCES:
Thies, "Chem. Abstracts," vol. 75 (1971), No. 63797j.
Thies, "Chem. Abstracts," vol. 76 (1972), No. 59634g.

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