2,8-disubstituted quinazolinones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544289, A61K 31505, C07D23980

Patent

active

057212384

ABSTRACT:
2,8-Disubstituted quinazolinones are prepared by first subjecting the quinazolinone basic skeleton to condensation by customary reactions and then introducing the desired substituents into the 8-position. The compounds are suitable as active compounds in medicaments, in particular for the treatment of inflammations, thromboembolic diseases and cardiovascular diseases.

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patent: 5482941 (1996-01-01), Terrett
S. Takano, et al., Heterocycles, vol. 29, No. 2, pp. 249-252, (1989).
M. Hoey, et al., Biochem. Pharmacol., vol. 40, pp. 193-202, (1990).

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