2,7-substituted octahydro-1H-pyrido[1,2-a]pyrazine...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C544S358000, C544S359000, C544S336000, C424S001650, C424S001110

Reexamination Certificate

active

10852611

ABSTRACT:
Substituted pyrido[1,2-a]pyrazines of general formula I; wherein Ar and Ar1represent various carbocyclic and heterocyclic aromatic rings; A represents O, S, SO, SO2, CHOH, C═O, or —(CR3R4); and n is 0–2, as well as precursors thereto, are ligands for dopamine receptor subtypes and serotonin (5HT) within the body and are therefore useful in the treatment of disorders of the dopamine and serotonin systems:

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