2,6-Dimethyl-4-2,3-disubstituted phenyl-1,4-dihydro-pyridine-3,5

Details 2,6-Dimethyl-4-2,3-disubstituted phenyl-1,4-dihydro-pyridine-3,5 2,6-Dimethyl-4-2,3-disubstituted phenyl-1,4-dihydro-pyridine-3,5

1979-06-19

1981-04-28

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546321, C07D21355, A61K 31455

Patent

active

042646111

ABSTRACT:
The present invention relates to new compounds having antihypertensive effect, which compounds are of the formula I, ##STR1## wherein R.sup.1 is selected from the group consisting of --CH.sub.3, --C.sub.2 H.sub.5, --CH.sub.2 CH.sub.2 OCH.sub.3, and --CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5, and R.sup.2 is selected from the group consisting of --C.sub.2 H.sub.5, --CH(CH.sub.3).sub.2, --C(CH.sub.3).sub.3, --CH(CH.sub.3)CH.sub.2 OCH.sub.3, C(CH.sub.3).sub.2 CH.sub.2 OCH.sub.3, and --CH.sub.2 C(CH.sub.3).dbd.CH.sub.2, whereby R.sup.1 and R.sup.2 are not the same, R.sup.3 is selected from the group consisting of chloro, and R.sup.4 is selected from the group consisting of chloro, and methyl, a method for lowering the blood pressure in mammals including man using said compounds, and pharmaceutical preparations containing said compounds.

REFERENCES:
patent: 3441648 (1969-04-01), Loev et al.
patent: 3488359 (1970-01-01), Bossert et al.
patent: 3799936 (1974-05-01), Meyer et al.

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