2,6-Dimethyl-3,5-dicarbomethoxy-4-(ortho -di-fluoromethylthiophe

Details 2,6-Dimethyl-3,5-dicarbomethoxy-4-(ortho -di-fluoromethylthiophe 2,6-Dimethyl-3,5-dicarbomethoxy-4-(ortho -di-fluoromethylthiophe

1982-07-16

1984-03-06

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424266, C07D21355

Patent

active

044355742

ABSTRACT:
The present invention relates to derivatives of 1,4-dihydropyridine and, more specifically, to 2,6-dimethyl-3,5-dicarbomethoxy-4-(o-difluoromethylthiophenyl)-1,4-dihydro pyridine having the formula ##STR1## The proposed compound features pronounced hypotensive activity of prolonged duration and is capable of producing a coronarodilating effect while having low toxicity and being useful for treating diseases of the cardiovascular system.

REFERENCES:
patent: 3968117 (1976-07-01), Bossert et al.
Kastron et al., Chemical Abstracts, vol. 91, No. 19, Abst. No. 157,609g, Nov. 5, 1979.

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