2,6-diaryl pyridazinones with immunosuppressant activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544240, A61K 3150

Patent

active

055062288

ABSTRACT:
A class of 2,6-diarylpyridazinones of general structural formula I have been identified that exhibit exhibit immunosuppressant activity with human T-lymphocytes, and are useful as an immunosuppressants. ##STR1## or a pharmaceutically acceptable salt, hydrate or crystal form thereof, wherein:

REFERENCES:
patent: 4545810 (1985-10-01), Pyne et al.
patent: 5059599 (1991-01-01), Mouzin et al.

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