Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1974-11-13
1976-05-25
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424258, 424263, A61K 31455
Patent
active
039594742
ABSTRACT:
2,6-Diamino-1,4-dihydropyridines bearing carbonyl functions in the 3- and 5-positions and being substituted in the 4-position by lower alkyl, phenyl, substituted phenyl or a heterocyclic group are antihypertensive agents and coronary vessel dilators. The compounds, of which 2,6-diamino-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-diethyl ester is a representative embodiment, are prepared through condensation of an amidine with either an aldehyde or an ylidenecyanoacetoacetic acid ester.
REFERENCES:
patent: 3708489 (1973-01-01), Rucker et al.
patent: 3773773 (1973-11-01), Bossert
patent: 3775422 (1973-11-01), Bossert
Bossert Friedrich
Meyer Horst
Stoepel Kurt
Vater Wulf
Bayer Aktiengesellschaft
Schenkman Leonard
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