2,6-Benzyl substituted phenols

Details 2,6-Benzyl substituted phenols 2,6-Benzyl substituted phenols

1979-03-30

1981-08-04

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568640, 568641, 568586, 568707, C07C 3915

Patent

active

042823900

ABSTRACT:
A process for killing internal parasites of warm blooded animals which process comprises treating the infected animal with an effective amount of a composition comprising as active ingredient a compound of the general formula I: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, are hydrogen, lower alkyl, lower alkenyl, lower alkanoyl, lower alkenoyl, aroyl or CH.sub.2 COOR.sup.4 wherein R.sup.4 is hydrogen or lower alkyl; B, C and D, which may be the same or different, are halogen, optionally substituted lower alkyl, optionally substituted aryl, lower alkenyl, lower alkoxy, hydroxy, cyano, nitro, or COR.sup.5 wherein R.sup.5 is hydroxy, lower alkoxy or NR.sup.6 R.sup.7 wherein R.sup.6 and R.sup.7, which may be the same or different, are hydrogen or lower alkyl; A, E, X, Y and Z, which may be the same or different, are hydrogen, halogen, optionally substituted lower alkyl, optionally substituted aryl, lower alkenyl, lower alkoxy, hydroxy, cyano, nitro, or COR.sup.5 wherein R.sup.5 is as hereinbefore defined; J and G, which may be the same or different, are hydrogen, lower alkyl, optionally substituted aryl, cyano, nitro or trichloromethyl or, together with the geminal hydrogen, the group .dbd.CCl.sub.2 ; or an optical isomer thereof; or a salt thereof; and wherein lower alkyl and lower alkoxy are defined as groups containing from 1 to 6 carbon atoms, lower alkenyl and lower alkanoyl are defined as groups containing from 2 to 6 carbon atoms and lower alkenoyl is defined as a group containing from 3 to 6 carbon atoms; and an inert carrier therefor.

REFERENCES:
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patent: 2735872 (1956-02-01), Beaver et al.
patent: 3067259 (1962-12-01), Bailey
patent: 3076783 (1963-02-01), Weaver
patent: 3330873 (1967-07-01), Godin et al.
patent: 3830850 (1974-08-01), Stratton
Manecke et al, Makromol. Chem., vol. 52, (1962), pp. 147-163.
Finn et al, Jour. Applied Chem., vol. 1, (1951), pp. 524-526.
Beaver et al, (I), Jour. Amer. Chem. Soc., vol. 75, (1953), pp. 5579-5581.
Foster et al, Jour. Org. Chem., vol. 26, (1961), pp. 2539-2541.

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