2,6,7-trisubstituted-3-methylenebicyclo(3.3.0)-octanes, and proc

Details 2,6,7-trisubstituted-3-methylenebicyclo(3.3.0)-octanes, and proc 2,6,7-trisubstituted-3-methylenebicyclo(3.3.0)-octanes, and proc

1986-09-11

1994-02-01

Shaver, Paul F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Silicon containing

556443, 556445, 556446, 568 15, 568 28, 568 31, 568 33, 568374, 568591, 568665, 560256, 549214, 549421, 549475, C07F 708, C07F 718

Patent

active

052833496

ABSTRACT:
A 2,6,7-trisubstituted-3-methylenebicyclo-[3.3.0]octane of formula (I) or an enantiomer thereof, or a mixture of these in an arbitrary ratio. The compound is a key intermediate for preparation of isocarbacyclins which are useful as medicines for the circulatory system such as an antithrombotic agent, an antilipidemic agent, a hypotensive agent or an antiarterosclerotic agent.

REFERENCES:
patent: 4346041 (1982-08-01), Aristoff
patent: 4359581 (1982-11-01), Skuballa et al.
patent: 4505905 (1985-03-01), Boswell et al.
patent: 4554363 (1985-11-01), Vorbrueggen
patent: 4644068 (1987-02-01), Shibasaki et al.
patent: 4681951 (1987-07-01), Shibasaki et al.
The Journal of the Chemical Society, Chemical Communications, No. 23, Aug. 1984, pp. 1602-1603.
Chemical Abstracts, vol. 103, No. 25, Feb. 1985, p. 871.

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