2',5'-phosphorothioate/phosphodiester oligoadenylates and anti-v

Details 2',5'-phosphorothioate/phosphodiester oligoadenylates and anti-v 2',5'-phosphorothioate/phosphodiester oligoadenylates and anti-v

1997-01-08

1999-01-26

Wilson, James O.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514885, 514889, 514934, 536 252, 536 256, 536 264, 530322, 530395, A61K 3170, C07H 2100

Patent

active

058639055

ABSTRACT:
Optically active antiviral compounds having the formula ##STR1## wherein m is 0, 1, 2, or 3; n and q are selected from the group of 0 and 1, provided that n and q may not both be zero; and R, R.sub.1, and R.sub.2 are independently of each other selected from the group consisting of oxygen and sulfur, provided that all R, R.sub.1 and R.sub.2, may not be oxygen, and further provided that all R, R.sub.1, and R.sub.2 may not be sulfur. The compounds possess increased antiviral activity and/or metabolic stability.

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