Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides containing saccharide radicals – e.g. – bleomycins – etc.
Patent
1992-07-16
1995-04-11
Rollins, John W.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Peptides containing saccharide radicals, e.g., bleomycins, etc.
536 252, 514 44, 530395, 525 542, C07K 900, C07H 2102
Patent
active
054059399
ABSTRACT:
Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages is of the Sp configuration possess increased antiviral activity and/or metabolic stability.
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Pfleiderer Wolfgang
Suhadolnik Robert J.
Crane L. Eric
Rollins John W.
Temple University Of The Commonwealth System Of Higher Education
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