Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1984-04-27
1985-09-03
Love, Ethel G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
A61K 3170
Patent
active
045393133
ABSTRACT:
3'-deoxyadenosine 5'-triphosphate is oligomerized to form (2'-5')-oligo (3'-deoxyadenylate) by incubation with adenosine triphosphate: (2'-5')-oligo adenosine adenyl transferase, in the presence of an inert support carrying a double stranded polynucleotide. The (2'-5')-oligo (3'-deoxyadenylate) is digested with a suitable phosphatase to remove the terminal phosphate groups. The thus produced corresponding 3'-deoxyadenosine compound is an anti-viral material effective against Herpes simplex infection and effective in inhibiting the transformation of cells infected with Epstein Barr virus.
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patent: 3337530 (1967-08-01), Hanze
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patent: 4210746 (1980-07-01), Kerr et al.
patent: 4315001 (1982-02-01), Blough
patent: 4378352 (1983-03-01), Kimchi et al.
Doetsch Paul
Henderson Earl E.
Suhadolnik Robert J.
Wu Joseph M.
Love Ethel G.
Research Corporation
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