Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2007-06-12
2007-06-12
Ramirez, Delia M. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S069100, C435S025000, C435S320100, C435S252300, C435S136000, C435S091100, C536S023100, C536S023200, C530S350000
Reexamination Certificate
active
10343369
ABSTRACT:
The invention provides isolated nucleic acid molecules encoding polypeptides having 2,5-DKG permease activity, and oligonucleotides therefrom. The isolated nucleic acid molecules can be expressed in appropriate bacterial cells to enhance the production of 2-KLG, which can subsequently be converted to ascorbic acid. Further provided are isolated polypeptides having 2,5-DKG permease acitivity, immunogenic peptides therefrom, and antibodies specific therefor. The invention also provides methods of identifying novel 2,5-DKG permeases.
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Dartois Veronique A.
Hoch James A.
Kumar Manoj
Valle Fernando
E.P.I. Liquidation Co.
Genencor International Inc.
Marcus-Wyner Lynn
Ramirez Delia M.
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