2,5-Dideoxystreptamine and the production thereof

Details 2,5-Dideoxystreptamine and the production thereof 2,5-Dideoxystreptamine and the production thereof

1974-10-15

1976-05-25

Curtis, Allen B.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260563D, 260309, 195 80R, C07B 9114

Patent

active

039593754

ABSTRACT:
2,5-Dideoxystreptamine is provided which is a new compound useful in the fermentative production of 5-deoxyneamine having useful antibacterial activity by culturing a microorganism. The production of 2,5-dideoxystreptamine is made by catalytic hydrogenation of 6,7-diaza-bicyclo[3.2.1]octane-2,4-diol which is also a new compound.

REFERENCES:
chem. Abs. 11157t 2-Deoxystreptamine Vol. 66, 1967 M. Nakajima.
J. Am. Chem. Soc. Vol. 74, 6/1952, pp. 3187, 3188, The Identity of Neamine & Neomycin A, Leach et al.
J. Am. Chem. Soc. Vol. 73, 2/1951, pp. 881, 882, Kuehl et al., "Streptomyces Antibiotics."

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