Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1998-03-16
1999-07-20
Davis, Zinna Northington
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C07C26100
Patent
active
059257806
ABSTRACT:
The present invention provides 2,5-diamino-3,4-disubstituted-1,6-diphenylhexane (DAD) isosteres comprising benzamide, sulfonamide and anthranilamide subunits, a pharmaceutical composition comprising such compounds, a method of using such compounds to treat retroviral, specifically HIV and more specifically HIV-1 and HIV-2, infections in mammals, particularly humans, a method of synthesizing asymmetric DAD isosteres comprising benzamide, sulfonamide and anthranilamide subunits, and a method of using such compounds to assay new compounds for antiretroviral activity.
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Erickson John W.
Randad Ramnarayan S.
Davis Zinna Northington
The United States of America as represented by the Department of
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