2,5,6,7-tetranor-4,8-inter-m-phenylene PGI.sub.2 derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514337, 514444, 546269, 549 60, 549458, A61K 31335, C07D30793

Patent

active

047756926

ABSTRACT:
Disclosed herein are novel prostaglandin I.sub.2 (PGI.sub.2) derivatives exhibiting excellent in vivo duration and activities, said derivatives being represented by the general formula: ##STR1## wherein R.sub.1, X, R.sub.2 and R.sub.3 are as defined herein.

REFERENCES:
patent: 4301164 (1981-11-01), Ohno et al.
patent: 4474802 (1984-10-01), Ohno et al.
patent: 4564620 (1986-01-01), Ohno et al.

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