2,4-Pyrimidine-dicarbamate-3-oxides

Details 2,4-Pyrimidine-dicarbamate-3-oxides 2,4-Pyrimidine-dicarbamate-3-oxides

1978-12-26

1979-11-27

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

544323, 544324, C07D23950, C07D40104, C07D40304

Patent

active

041761197

ABSTRACT:
Oxadiazolopyrimidine derivatives of the formula ##STR1## wherein R and R.sub.1 are as hereinafter described, prepared, inter alia, by cyclizing a compound of the formula ##STR2## wherein R and R.sub.1 are as hereinafter described. The end products are useful in the treatment of vascular-conditioned hypertension or as vasodilators in the case of peripheral blood supply disorders.

REFERENCES:
patent: 3973016 (1976-08-01), Morrison et al.
patent: 4098791 (1978-07-01), Hylton et al.
Dyer et al., J. Med. Chem., vol. 8 (2) pp. 195-200 (1965).

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