2-[4-(Polyhalo-2-hydroxy-2-propyl)anilino]thiazolin-4-ones

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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424270, C07D27704

Patent

active

041761200

ABSTRACT:
2-[4-(Polyhalo-2-hydroxy-2-propyl)anilino]-2-oxazolin-4-ones and the thiazolin-4-ones corresponding thereto, having useful anti-hypertensive properties, are disclosed herein. The compounds are prepared by reaction of the appropriate 4-(polyhalo-2-hydroxy-2-propyl)aniline with a .beta.-chloroethanoyl isocyanate or isothiocyanate and then cyclization of the resultant intermediate.

REFERENCES:
patent: 4071528 (1978-01-01), Dalton et al.
patent: 4081547 (1978-03-01), Neustadt
patent: 4103018 (1978-07-01), Neustadt et al.

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