Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1997-08-20
1999-06-29
Lambkin, Deborah C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560 8, 562490, 562405, C07C 6976, C07C 6336
Patent
active
059170824
ABSTRACT:
Enantiomerically substantially pure compounds of the formula ##STR1## where R is H or lower alkyl of 1 to 6 carbons, or pharmaceutically acceptable salts thereof have retinoid-like biological activity. The enantimerically pure or substantially pure compound of the above formula where R is H, or a pharmaceutically acceptable salt thereof, is highly specific agonist of RXR retinoid receptors in preference over RAR receptors.
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Chandraratna Roshantha A.
Vuligonda Vidyasagar
Allergan Sales Inc.
Baran Robert J.
Lambkin Deborah C.
Szekeres Gabor L.
Voet Martin A.
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