2,4-pentadienoic acid derivatives and platelet aggregation inhib

Details 2,4-pentadienoic acid derivatives and platelet aggregation inhib 2,4-pentadienoic acid derivatives and platelet aggregation inhib

1987-03-10

1988-08-16

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

2604105, 2604109R, 260413, 2605011, 560116, 560119, 562498, 562501, C07C 5946, A61K 3119

Patent

active

047645288

ABSTRACT:
Novel 2,4-pentadienoic acid derivatives are disclosed. As the examples are mentioned 3-(4-carboxy-trans, trans-1,3-butadienyl)-6-exo-(3.alpha.-hydroxy-trans-1-octenyl)-7-endo-hydr oxybicyclo[3.3.0]oct-2-ene, 3-(5-carboxy-trans, trans-2,4-pentadienyl)-6-exo-(3.alpha.-hydroxy-trans-1-octenyl)-7-endo-hyd roxybicyclo[3.3.0]oct-2-ene and the like. These compounds are useful as a platelet aggregation inhibitor, especially as a thrombosis-prophylactic agent.

REFERENCES:
patent: 4588823 (1986-05-01), Aristoff

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