[2-(4-Oxo-4H-1-benzopyran-2-yl)ethenyl]benzonitriles and benzoic

Details [2-(4-Oxo-4H-1-benzopyran-2-yl)ethenyl]benzonitriles and benzoic [2-(4-Oxo-4H-1-benzopyran-2-yl)ethenyl]benzonitriles and benzoic

1975-11-20

1977-07-05

Demers, Arthur P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603452, 2603455, 424283, C07D31122

Patent

active

040338452

ABSTRACT:
The present invention relates to [2-(4-oxo-4H-1-benzopyran-2-yl)ethenyl]benzonitrile and benzoic acids having the following structural formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are hydrogen, lower alkyl, halogen or lower alkoxy, and A is COOH or CN. The compounds of this invention exhibit anti-allergy properties and are indicated in the management of allergic manifestations such as bronchial asthma.

REFERENCES:
patent: 3598840 (1971-08-01), Majoie
patent: 3786071 (1974-01-01), Cairns et al.
patent: 3825574 (1974-07-01), Brown
patent: 3872108 (1975-03-01), Ukyo et al.
patent: 3896114 (1975-07-01), Nohara et al.
Koo, J. Org. Chem. 26 (1961) pp. 2440-2442.

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