2-(4-imidazoyl) cyclopropyl derivatives

Details 2-(4-imidazoyl) cyclopropyl derivatives 2-(4-imidazoyl) cyclopropyl derivatives

1995-05-30

1997-07-29

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5483381, 5483401, 5483411, 5483415, 5483421, 5483451, A61K 31415, C07D23364, C07D23356

Patent

active

056522584

ABSTRACT:
The present invention provides compounds having H.sub.3 histamine receptor antagonist activity of the general formula: ##STR1## where X is H, A is --CH.sub.2 CH.sub.2 --, --COCH.sub.2 --, --CONH--, --CON(CH.sub.3)--, --CH.dbd.CH--, --C.tbd.C--, --CH.sub.2 --NH--, --CH.sub.2 --NCH.sub.3 --, --CH(OH)CH.sub.2 --, --NH--CH.sub.2 --, --N(CH.sub.3) --CH.sub.2 --, --NHSO.sub.2 --, --CH.sub.2 O--, --CH.sub.2 S--, CH.sub.2 SO.sub.2 --, or --CH.sub.2 S(O)--;

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