Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-02-25
1984-09-04
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544121, 544360, 544362, 544398, 544399, A61K 31495, C07D24104
Patent
active
044696957
ABSTRACT:
2-(4-Hydroxyalkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions of the derivatives are disclosed. The derivatives exhibit dopamine-receptor stimulating activity in a mammal and are useful for treating hyperprolactinemia, galactorrhea, amenorrhea, impotence, Parkinsonism, diabetes, acromegaly, hypertension and other central nervous system disorders.
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Toda et al., "Chemical Abstracts", vol. 76, 1972, col. 72185f.
Biggi et al., "J. Amer. Chem. Soc.", vol. 95, 1973, pp. 7101-7107.
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Nozoe et al., "Chemical Abstracts", vol. 70, 1969, col. 87244z.
Bagli Jehan F.
Bogri Tibor
Voith Katherine
Ayerst McKenna & Harrison, Inc.
Daus Donald G.
Turnipseed James H.
Wilfond Arthur E.
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