2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as

Details 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as

1995-04-24

1995-12-12

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514658, 562 62, 564282, A61K 31185

Patent

active

054750326

ABSTRACT:
2,4-disulfonyl .alpha.-phenyl-tert-butyl nitrone and its pharmaceutically acceptable salts are disclosed. These materials are useful as pharmaceutical agents for oral or parenteral, e.g. intravenous administration to patients suffering from acute central nervous system oxidation as occurs in a stroke or from gradual central nervous system oxidation which can exhibit itself as progressive central nervous system function loss. The materials are also used to ameliorate the side effects of oxidative-damage causing antineoplastic disease treatments.

REFERENCES:
patent: 5025032 (1991-06-01), Carney et al.
patent: 5036097 (1991-07-01), Floyd et al.

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