2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts,

Details 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts, 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts,

1983-07-12

1985-07-09

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544396, A61K 31495, C07D24104

Patent

active

045281947

ABSTRACT:
A piperazine derivative of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom or a lower alkyl group; R.sup.2 is a hydroxyl group, an aralkyloxy group, a lower alkoxy group containing 1-5 carbon atoms or a lower alkenyloxy group containing 3-5 carbon atoms; R.sup.3 is a hydrogen atom, or an aralkyloxy group, a lower alkoxy group containing 1-5 carbon atoms or a lower alkenyloxy group containing 3-5 carbon atoms; and R.sup.4 is a hydrogen atom or a lower alkoxy group containing 1-5 carbon atoms, provided that R.sup.2 is a group other than the lower alkoxy group containing 1-5 carbon atoms when both R.sup.3 and R.sup.4 are hydrogen atoms; or a pharmaceutically acceptable salt is effectively useful as a cerebral circulation-improving agent.

REFERENCES:
patent: 3505334 (1970-04-01), Regnier et al.
patent: 3868377 (1975-02-01), Raabe et al.
Raynaud et al, Chem. Abst., vol. 74, 1971, p. 318, 22882u.

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