[[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcepha

Details [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcepha [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcepha

1976-03-30

1977-12-13

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, 544 21, 2603322A, 548311, 548309, C07D50136

Patent

active

040630196

ABSTRACT:
[[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives having the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl, a salt forming ion, or the group ##STR2## R.sub.1 is hydrogen or methoxy; R.sub.2, R.sub.3 and R.sub.5 each is hydrogen or lower alkyl; R.sub.4 is hydrogen, lower alkyl, cyclo-lower alkyl, cyclo-lower alkenyl, cyclo-lower alkadienyl, phenyl, phenyl-lower alkyl, substituted phenyl, substituted phenyl-lower alkyl, or certain heterocyclic groups; R.sub.6 is lower alkyl; and X is hydrogen, lower alkanoyloxy, ##STR3## or certain heterothio groups; are useful as antibacterial agents.

REFERENCES:
patent: 3708479 (1973-01-01), Welch et al.
patent: 3925368 (1975-12-01), Cooper et al.
patent: 3956288 (1976-05-01), Bambury

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