2,4-dihydroxyadipic acid derivative

Details 2,4-dihydroxyadipic acid derivative 2,4-dihydroxyadipic acid derivative

1991-07-02

1993-05-25

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560180, 560146, 560186, 562582, 562578, 562587, 549449, 549375, 556437, C07C 6966

Patent

active

052141977

ABSTRACT:
A novel 2,4-dihydroxyadipic acid derivative of the formula: ##STR1## wherein R.sup.1 and R.sup.4 are the same or different and each a hydrogen atom, an alkyl group, an aralkyl group, an aryl group or a silyl group, and R.sup.2 and R.sup.3 are the same or different and each a hydrogen atom or a protective group of a hydroxy group or together form a ring, which is useful as a common intermediate in the synthesis of HMG-CoA reductase inhibitor.

REFERENCES:
Suemune, H. et al., Tetrahedron Asymmetry vol. 1, No. 7, pp. 425-428 1990.
Chemical Abstracts, vol. 114, No. 5, Feb. 4, 1991, Abstract No. 42336s.

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