2,4-dihydroxy-3,5,6-trimethylbenzoic acid compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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C07C 6988

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active

051420961

ABSTRACT:
KS-506a, KS-506x and KS-506g having an activity to inhibit cyclic nucleotide phosphodiesterase and KS-506m and KS-506h having an activity to inhibit histamine release are produced by culturing a microorganism belonging to the genus Mortierella.

REFERENCES:
patent: 4119432 (1978-10-01), Gaughan
patent: 4555402 (1985-11-01), Matsuda et al.
Tereferol--J. Antibiot., 37, 6-9 (1984).
Griseolic Acid--J. Antibiot., 38, 832 (1985).
Reticurol--J. Antibiot., 28, 558-560 (1975).
PDE-I, II--Arg. Biol. Chem., 42, 1331-1336 (1978).
KS-619-1--J. Antibiot., 40, 1104-1110 (1987).
KS-259-2--J. Antibiot., 40, 1092-1100 (1987).
Genistein--Agr. Biol. Chem., 51, 3003-3009 (1987).
Elix et al., "Five New Fully Substituted Depsides from the Lichen", pp. 2023-2029; (1987).
Chemical Abstracts, vol. 108; p. 434 (1968).

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