2,4-Dihydr o-2(omega-aminoalkyl)-1H-[1,2,4]triazolo[3,4-c]benzox

Details 2,4-Dihydr o-2(omega-aminoalkyl)-1H-[1,2,4]triazolo[3,4-c]benzox 2,4-Dihydr o-2(omega-aminoalkyl)-1H-[1,2,4]triazolo[3,4-c]benzox

1984-05-10

1985-10-15

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544101, A61K 31535, C07D49804

Patent

active

045474990

ABSTRACT:
2,4-Dihydro-2-(omega-aminoalkyl)-1H-[1,2,4]triazolo[3,4-c][1,4]benzoxazin-1 -ones of the formula ##STR1## where n and -NRR are as defined in the specification, e.g., 2-[4-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)piperadinyl]butyl]-2,4-dih ydro-1H-[1,2,4]triazolo[3,4-c][1,4]benzoxazin-1-one, are disclosed. They are useful for treating hypertension or allergy conditions in humans and valuable animals.

REFERENCES:
patent: 3846421 (1974-11-01), Meguro et al.
patent: 3850951 (1974-11-01), Meguro et al.
patent: 3987052 (1976-10-01), Hester, Jr.
patent: 4250094 (1981-02-01), Hester, Jr.
J. Chem. Soc., (London), 1928, Part II, "The Synthesis . . . 1,4-Benzisooxazines", by G. Newberry et al., pp. 3046-3050.
Zhurnal Organichesskoi Khimii, 2, (1966), pp. 1478-1482; (Eng. Trans. 2, pp. 1461-1464).

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