2,4-Diaminoquinazolines as antithrombotic agents

Details 2,4-Diaminoquinazolines as antithrombotic agents 2,4-Diaminoquinazolines as antithrombotic agents

1973-10-30

1976-05-11

Drezin, Norman A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602564Q, 2602475DP, A61K 31505

Patent

active

039564959

ABSTRACT:
2,4-diaminoquinazolines are employed as antithrombotic agents and have the following general formula: ##SPC1##
Wherein R.sub.1 and R.sub.2 are monovalent groups independently selected from the group consisting of ##EQU1## wherein R.sub.4 and R.sub.5 independently are selected from the group consisting of hydrogen, alkyl, and cycloalkyl, with the proviso that both R.sub.4 and R.sub.5 cannot be cycloalkyl, ##EQU2## wherein R.sub.6, R.sub.7, and R.sub.8 independently are selected from the group consisting of hydrogen and alkyl, and A is a divalent organic group having from two to about six carbon atoms such that the two nitrogen atoms are separated by at least two carbon atoms, and

REFERENCES:
patent: 2794018 (1957-05-01), Spinks et al.
patent: 2945859 (1960-07-01), Hitchings et al.
patent: 3511836 (1970-05-01), Hess

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