2,4-Diamino-6-methyl-5-(halophenylazo) pyrimidines

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424226, C07C10704

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active

040838412

ABSTRACT:
Compounds comprising selected 2,4-diamino-6-methyl-5-(halophenylazo) pyrimidines which are highly active as folic acid antagonists. The compounds include 2,4-diamino-6-methyl-5-(m-chlorophenylazo) pyrimidine; 2,4-diamino-6-methyl-5-(p-bromophenylazo) pyrimidine; and 2,4-diamino-6-methyl-5-(p-iodophenylazo) pyrimidine.

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Merck Index, Eighth Ed., Merck & Co., Inc.:Rahway, N. J. 1968, "Pyrimethamine", pp. 892-893.
Lythgoe et al., Chemical Abstracts, 38:5837.sup.8.
Fidler et al., Chemical Abstracts, 52:7328g.

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