2,4-Diamino-5-(4'-methylthio)benzylpyrimidenes, compounds, compo

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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540122, 42424856, 544325, C07D23948, A61K 31505

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active

041805780

ABSTRACT:
A compound selected from a 2,4-diamino-5-thiobenzylpyrimidine of the formula: ##STR1## in which R is selected from hydrogen, alkyl, lower alkoxy, and halogen and R' is alkyl; and pharmacologically acceptable acid addition salts thereof. These compounds have an anti-bacterial action and are sulphonamide potentiators.

REFERENCES:
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patent: 3822264 (1974-07-01), Roth
patent: 3850927 (1974-11-01), Cresswell
patent: 3852276 (1974-12-01), Cresswell
patent: 3855265 (1974-12-01), Cresswell
patent: 4076810 (1978-02-01), Kompis
Bushby, S. and G. Hitchings, "Br. J. Pharmac. Chemother.", (1968), 33, pp. 72-90.

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