2,4,DI (hetero-) arylamino (-oxy)-5-substituted pyrimidines...

Details 2,4,DI (hetero-) arylamino (-oxy)-5-substituted pyrimidines... 2,4,DI (hetero-) arylamino (-oxy)-5-substituted pyrimidines...

2006-06-27

2006-06-27

Balasubramanian, Venkataraman (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S275000, C544S323000, C544S324000, C544S325000, C544S321000, C544S326000, C544S327000, C544S328000

Reexamination Certificate

active

07067522

ABSTRACT:
Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.

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