Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2006-03-28
2006-03-28
Richter, Johann (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C514S235800, C514S317000, C514S326000, C514S381000, C514S524000, C514S534000, C514S567000, C558S418000, C548S254000, C548S950000, C546S210000, C546S229000, C544S392000, C544S366000, C560S019000, C562S433000, C562S456000
Reexamination Certificate
active
07019033
ABSTRACT:
Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of the formulawhere R1, R2, R3, R4, R5, and R6are hydrogen or substituent groups such as alkyl, and where R7is hydrogen or an organic radical, and Z is COOR7, tetrazolyl, CONR6R7, or CH2OR7, are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as inflammation, psoriasis and restenosis, as well as stroke, heart failure, and immunodeficiency disorders.
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Barrett Stephen Douglas
Bridges Alexander James
Cody Donna Reynolds
Doherty Annette Marian
Dudley David Thomas
Richardson Peter C.
Sackey Ebenezer
Warner-Lambert & Company
Yakovleva Galina M.
Zielinski Bryan C.
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