Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-05
1997-03-25
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5462684, C07D40104, A61K 3144, A61K 3141
Patent
active
056145373
ABSTRACT:
The invention relates 2,4- and 2,5-bistetrazolylpyridines. Said compounds inhibit the enzymes proline hydroxylase and lysine hydroxylase and bring about a selective inhibition of collagen biosynthesis. They are used as fibrosuppressants and immunosuppressants.
REFERENCES:
patent: 4717727 (1988-01-01), Gunzler et al.
patent: 4968670 (1990-11-01), Brocks et al.
patent: 5013736 (1991-05-01), Nagahara et al.
patent: 5037839 (1991-08-01), Bickel et al.
patent: 5364873 (1994-11-01), Bickel
M. Haring et al., Helvetica Chemica Acta, 37(17):147-153 (1954).
T. Itai et al., Bulletin Nat'l Institute of Hygiene, 74:115-117 (1956).
Shinohara et al., Chemistry High Polymers, Japan 15:839-849 (1958).
T. Hirakata et al., J. Pharm. Soc. Japan, 77:219:221 (1957).
K. Majamaa et al., Eur. J. Biochem, 138:329-245 (1984).
G. Tschank et al., Biochem, J., 248:625-633 (1987).
Baader Ekkehard
Bickel Martin
G unzler-Pukall Volkmar
Schubert Gerrit
Hoechst Aktiengesellschaft
Ivy C. Warren
M. Mach D. Margaret
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