2,4,7-substituted 5-hydroxy benzopyrans and esters

Details 2,4,7-substituted 5-hydroxy benzopyrans and esters 2,4,7-substituted 5-hydroxy benzopyrans and esters

1974-05-22

1976-03-30

Drezin, Norman A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602472A, 2602935S, 260297B, 424246, 424248, 424263, C07D31160

Patent

active

039474623

ABSTRACT:
2,4,7-Substituted 5-hydroxy benzopyrans and dihydrobenzopyrans and their esters represented by the formulae ##SPC1##
Wherein each R.sub.1 is loweralkyl, and R.sub.2 is hydrogen, loweralkanoyl or ##SPC2##
With Y being a straight or branched chain alkylene group having from 1-8 carbon atoms; a is an integer from 1-4; b is an integer from 1-4; X is CH.sub.2, O, S, or NR.sub.5 with R.sub.5 being hydrogen or loweralkyl, with the limitation that when X is O, S, or NR.sub.5, the sum of a and b is 3 or 4 and R.sub.4 is hydrogen or loweralkyl; and R.sub.3 is ##SPC3##
With Y' being a straight or branched chain alkylene group having from 1-10 carbon atoms; and each R.sub.7, R.sub.8 and R.sub.9 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl and the pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 3707474 (1972-12-01), Razdan et al.
patent: 3726883 (1973-04-01), Razdan et al.
patent: 3804841 (1974-04-01), Razdan et al.
patent: 3853899 (1974-12-01), Fake

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