Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1979-07-30
1981-12-29
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424263, 546278, 548348, 548351, C07D23330, C07D40104, A61K 31415
Patent
active
043082777
ABSTRACT:
Compounds of the formula ##STR1## in which R.sub.1 and R.sub.2 independently of one another are substituted or unsubstituted aryl or hetero-aryl groups, R.sub.3 is hydrogen or lower alkyl and R.sub.4 is a substituted or unsubstituted aliphatic hydrocarbon radical, and their pharmaceutically usable salts. These compounds possess immunoregulatory, antithrombotic and antiinflammatory properties and can be used as active ingredients in medicaments. They are prepared, for example, by reacting compounds of the formulae ##STR2## in which one of the radicals X and Y is mercapto, which can be in the form of a salt, and the other is a radical replaceable by etherified mercapto, with one another.
REFERENCES:
patent: 2981739 (1961-04-01), Bimber
patent: 4182769 (1980-01-01), Cherkofsky et al.
patent: 4190666 (1980-02-01), Cherkofsky et al.
Ferrini Pier G.
Goschke Richard
Almaula Prabodh I.
Ciba-Geigy Corporation
Rotman Alan L.
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