2,4,5-Trichlorophenol process

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568776, C07C 3932, C07C 3700

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active

042373212

ABSTRACT:
A method of making 2,4,5-trichlorophenol by chlorinating 2,5-dichlorophenol is characterized by reacting 2,5-dichlorophenol with chlorine in the presence of a liquid inert polar aprotic reaction medium such as nitrobenzene or a chlorinated hydrocarbon reaction medium, particularly 1,2-dichloroethane, and preferable a Lewis acid catalyst, particularly aluminium chloride. The product contains a higher ratio of 2,4,5-trichlorophenol to 2,3,6-trichlorophenol than has been obtainable previously.

REFERENCES:
patent: 2494993 (1950-01-01), Foster
patent: 2665314 (1954-01-01), Krantz
patent: 3318949 (1967-05-01), Roberts
Groves, et al. "Journal of the Chemical Society", (1929), pp. 512-513.
Galat, "Journal of the American Chemical Society", (1952), 74 pp. 3890-3891.
Merck Index 9th Ed., Merck Co., Inc. pp. 4546, 9322 & 9324 (1976).

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