2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine

Details 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine

1977-03-08

1980-03-18

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602433, 424246, 42424856, 544 60, 544120, 544405, 544408, 544 586, A61K 31495, C07D24118

Patent

active

041939956

ABSTRACT:
2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds optionally having substituents in the 5 and/or 6 positions, possessing .beta.-adrenergic blocking properties are described. The products are prepared by reaction of a 2-chloro(or hydroxy)pyrazine with a 5-hydroxymethyl(or sulfonyloxymethyl)oxazolidine followed by acid hydrolysis.

REFERENCES:
patent: 4027027 (1977-05-01), Jaeggi et al.

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