2-(3-Substituted amino-2-hydroxypropoxy)-3-piperidino pyrazines

Details 2-(3-Substituted amino-2-hydroxypropoxy)-3-piperidino pyrazines 2-(3-Substituted amino-2-hydroxypropoxy)-3-piperidino pyrazines

1980-07-03

1982-08-10

Sutto, Anton H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544357, A61K 31495, C07D24118

Patent

active

043438024

ABSTRACT:
2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds optionally having substituents in the 5 and/or 6 positions, possessing .beta.-adrenergic blocking properties are described. The products are prepared by reaction of a 2-chloro (or hydroxy) pyrazine with a 5-hydroxymethyl (or sulfonyloxymethyl) oxazolidine followed by acid hydrolysis.

REFERENCES:
patent: 3946009 (1976-03-01), Wasson et al.
patent: 4042586 (1977-08-01), Wasson et al.
patent: 4193995 (1980-03-01), Wasson et al.

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