(2,3-dihydro-5-benzofuranyl)-acetonitrile

Details (2,3-dihydro-5-benzofuranyl)-acetonitrile (2,3-dihydro-5-benzofuranyl)-acetonitrile

1997-02-27

1997-12-02

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549469, C07D30779

Patent

active

056938314

ABSTRACT:
The novel compound (2,3-dihydro-5-benzofuranyl)-acetonitrile is prepared by chloromethylating 2,3-dihydro-benzofuran and reacting the resulting 2,3-dihydro-5-chloromethyl-benzofuran with a cyanide. (2,3-Dihydro-5-benzofuranyl)-acetonitrile can be converted by saponification to (2,3-dihydro-5-benzofuranyl)-acetic acid, an important intermediate for the manufacture of various pharmaceutical active substances. This intermediate has hitherto been obtainable only by a laborious procedure and in low yields.

REFERENCES:
"Antiinflammatory Activity of Some 2,3-Dihydrobenzofuran-5-Acetic Acids and Related Compounds," Hirose et al., J. Med. Chem., 1976, vol. 19, No. 2, pp. 303-308.

Affiliated with

Also associated with

Rating

(2,3-dihydro-5-benzofuranyl)-acetonitrile does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with (2,3-dihydro-5-benzofuranyl)-acetonitrile, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and (2,3-dihydro-5-benzofuranyl)-acetonitrile will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-803163