Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-08-11
1996-10-22
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5462771, C07D40104, A61K 3144
Patent
active
055677185
ABSTRACT:
2,3-dihydro-1H-isoindole derivatives of the formula ##STR1## where R.sub.1 -R.sub.5 and X are defined herein which are useful as serotonin reuptake inhibitors are disclosed. As such, these compounds may be useful for the treatment of depression, obsessive-compulsive disorders, stuttering and trichotillomania.
REFERENCES:
patent: 4124375 (1978-11-01), Bollinger et al.
Truitt, et al, New Compounds, vol. 8, 731 (Sep. 1965).
Suzuki, et al, J. Heterocyclic Chem., 16, 645 (1979).
Huffman, J. Heterocyclic Chem., 24, 549 (1987).
Hussein, et al, Asian Journal of Chemistry, vol. 3, No. 1, 30 (1991).
Bornstein, et al, "Organic Syntheses", 406-408.
Bornstein, et al, "(Organic Syntheses)", 1064-1066.
CA 109:6377 Moormann et al. 1987.
CA 118:30398 Rodier et al. 1992.
CA 115:49312 Hussein et al. 1991.
CA 115:136387 Hansen et al. 1991.
Whitaker et al. Annals of the New York Academy of Science, vol. 600, pp. 109-110. 1990.
Principles of Psychopharmacology. Clark et al. Academic Press. N.Y. 1970. pp. 166-167.
Kapples Kevin J.
Shutske Gregory M.
Fan Jane
Hoechst Marion Roussel Inc.
Maurer Barbara V.
LandOfFree
2,3-dihydro-1h-isoindole derivatives and their use as serotonin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2,3-dihydro-1h-isoindole derivatives and their use as serotonin , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2,3-dihydro-1h-isoindole derivatives and their use as serotonin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2358896