2,3-dihydro-1,4-benzodioxin-5-yl-piperazine derivatives having 5

Details 2,3-dihydro-1,4-benzodioxin-5-yl-piperazine derivatives having 5 2,3-dihydro-1,4-benzodioxin-5-yl-piperazine derivatives having 5

1994-06-30

1995-10-31

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544364, 544368, 544373, A61K 31495, C07D40514

Patent

active

054629420

ABSTRACT:
The present invention is concerned with compounds having 5-HT1A antagonistic activity useful in treating CNS disorders and having formula 2 ##STR1## wherein R.sub.1 is halogen, lower alkyl or alkoxy, hydroxy, trifluotomethyl or cyano,

REFERENCES:
patent: 4591590 (1986-05-01), Ueda et al.
patent: 4833142 (1989-05-01), Hartos et al.
patent: 5001130 (1991-03-01), New et al.

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