Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-12-22
1983-08-09
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
560124, 260465D, 2604654, 424304, 424305, 424308, 424251, 424263, 424267, 424270, 424272, 424273P, 424273R, 424275, 424285, 544335, 544399, 546248, 546335, 548203, 548214, 548236, 548248, 548342, 548353, 548367, 548377, 548572, 549 79, 549499, 560 1, 560105, 560122, A61K 31495, C07D23926, C07D21132, C07C 69612, C07C 69635
Patent
active
043978517
ABSTRACT:
Antimicrobial compounds of the formula: ##STR1## wherein Hal is bromine or chlorine; R is C.sub.1-4 alkyl, straight or branched chain; and one of R.sup.1 and R.sup.2 is hydrogen and the other is selected from the group consisting of C.sub.3-8 cycloalkyl; C.sub.3-8 cycloalkyl C.sub.1-3 alkyl; phenyl; phenyl C.sub.1-3 alkyl; mono- or disubstituted phenyl or phenyl C.sub.1-3 alkyl wherein the substituents are halo, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, hydroxy, nitro, cyano, or trifluoromethyl; a heterocyclic radical selected from the group consisting of thienyl, furanyl, pyrrolyl, isoxazolyl, oxazolyl, isothiazolyl, thiazolyl, pyrazolyl, imidazolyl, pyridazinyl, pyrimidinyl, pyrazinyl, and pyridinyl, and N-oxides thereof; and a saturated heterocyclic radical selected from the group consisting of pyrrolidinyl, tetrahydrofuranyl, tetrahydrothienyl, isoxazolidinyl, oxazolidinyl, isothiazolidinyl, thiazolidinyl, pyrazolidinyl, imidazolidinyl, piperazinyl, and piperidinyl.
REFERENCES:
patent: 2320034 (1943-05-01), D'Ianni
patent: 3317568 (1967-05-01), Wygant et al.
patent: 3608084 (1971-09-01), Matt
patent: 3833731 (1974-09-01), Grier et al.
patent: 3873597 (1975-03-01), Harmetz et al.
patent: 3877922 (1975-04-01), Grier et al.
patent: 4328363 (1982-05-01), Heiba et al.
Gershon, et al., J. Med. Chem. 20(4), 606-609, (1977), Chem Ab. 84:39698t.
Motoyama, et al., Sankyo Kenkyusho Nempo 23:233-244, (1971), Chem. Ab. 77:30239s.
Angeles Marshall R.
D'Errico Michael J.
Engelhart John E.
Clarke Vera C.
Merck & Co. , Inc.
Robertson Alice O.
Speer Raymond M.
Trousof Natalie
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