2,3-difluoro-6-nitrobenzonitrile and 2-chloro-5,6-difluorobenzon

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

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558424, 558425, 562493, C07C25314

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active

054789630

ABSTRACT:
The present invention describes the novel intermediates 2,3-difluoro-6-nitrobenzonitrile and 2-chloro-5,6-difluorobenzonitrile, a process for their preparation and their advantageous use for the preparation of 2,3,6-trifluorobenzoic acid, which in turn is a valuable intermediate for the preparation of insecticides and antibacterial agents. The intermediates according to the invention are prepared from 2,3,4-trifluoronitrobenzene by fluorine/cyanide exchange and subsequent denitrating chlorination. 2,3,6-Trifluorobenzoic acid can be prepared from the novel intermediates, in a manner known per se in the literature, by simple chlorine/fluorine exchange and subsequent hydrolysis in a process which overall is industrially advantageous and economically favorable.

REFERENCES:
patent: 4209457 (1980-06-01), Fuller
patent: 4225534 (1980-09-01), Yoshikawa
patent: 4229365 (1980-10-01), Oeser et al.
patent: 4582948 (1986-04-01), Tang et al.
patent: 4590315 (1986-05-01), Maul et al.
patent: 4684734 (1987-08-01), Kaieda et al.
Patent Abstract of Japan, Publication No. JP3090057, Application No. JP890225246, Apr. 16, 1991.

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