2',3'-dideoxy purine nucleoside

Details 2',3'-dideoxy purine nucleoside 2',3'-dideoxy purine nucleoside

1989-08-03

1991-10-01

Lilling, Herbert J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 22, 536 26, 435 88, 435847, 435849, 435852, A61K 3152, A61K 3170, C07D47316, C07D4054

Patent

active

050534998

ABSTRACT:
2', 3'-Dideoxy purine nucleosides represented by following general formulae [I] and/or [II] ##STR1## (wherein X and Y indicate nitrogen atoms or carbon atoms and R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 indicate each independently any of hydrogen atom, hydroxyl group, amino group, alkyl group, halogen atom, alkoxy group and mercapto group), process for the preparation thereof and applications thereof to the antiviral agent, antiretroviral agent, therapeutic drug and preventive drug for acquired immunodeficiency syndrome (AIDS), and experimental medicine and experimental reagent to be used in genetic engineering are claimed.

REFERENCES:
APP Environ Microbiol 55 (2) 419-24 (1989).
Chemical Pharmaceutical Bull 36 (10) 4153-6 (1988).
Synthesis (9) 670-4 (1988).
Nucleic Acids Symposium Series 20 17 (1988).

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