2',3'-Dideoxy-2'-fluoronucleosides

Details 2',3'-Dideoxy-2'-fluoronucleosides 2',3'-Dideoxy-2'-fluoronucleosides

1990-09-13

1992-06-30

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, C07H 1700

Patent

active

051265060

ABSTRACT:
There are disclosed novel 2',3'-dideoxy-2'-fluoronucleosides and 2'-3'-dideoxy-2',3'-didehydro-2'-fluoronucleosides and processes for their preparation. The compounds so produced exhibit therapeutically useful antiviral and, more particularly, anti-HIV effects.

REFERENCES:
Kinney-Thomas, et al. Biochem. Pharm 36: 311-316, 1987.
Mitsuya, et al. P.N.A.S. U.S.A. 83: 1911-1915, 1986.
Chem Eng. News, Oct. 23, 1987, pp. 44, 45 & 48.
Baba et al. Biochem & Biophys. Res. Comm. 142: 128-134, 1987.

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