2,3-diaryl-5-bromothiophene compounds of use for the treatment o

Details 2,3-diaryl-5-bromothiophene compounds of use for the treatment o 2,3-diaryl-5-bromothiophene compounds of use for the treatment o

1984-02-10

1989-04-11

Siegel, Alan

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 80, C07D33316, C07D33308

Patent

active

048208272

ABSTRACT:
A small group of 2,3-diaryl-5-bromothiophene compounds such as 5-bromo-2-(4-methylthiophenyl)-3-(4-fluorophenyl)thiophene have been found to possess significant and unexpected antiinflammatory activity, and inhibition of prostaglandin synthetase useful for the treatment of arthritis and dysmenorrhea.

REFERENCES:
patent: 2625553 (1953-01-01), Pines et al.
patent: 2639286 (1953-05-01), Mavity
patent: 4174405 (1979-11-01), Relyea et al.
patent: 4302461 (1981-11-01), Cherkofsky
patent: 4381311 (1983-04-01), Haber

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