2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salt

Details 2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salt 2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salt

1985-06-05

1986-12-16

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D51314

Patent

active

046297936

ABSTRACT:
Compounds of the formula wherein R is ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 are the same or different and are selected from the group consisting of hydrogen, chlorine, bromine, lower alkyl, lower alkoxy and naphthyl, provided that when R.sub.1 is lower alkyl, R.sub.2 and R.sub.3 are hydrogen, chlorine, bromine or lower alkoxy, or a pharmaceutically acceptable salt thereof, have anti-carrageenin edema activity, and are useful as anti-inflammatory agents and immuno modulators. They are produced by reacting an amide of the formula ##STR2## wherein R has the same meanings hereinabove, with N,N'-ethylene thiourea.

REFERENCES:
patent: 4103016 (1978-07-01), Moser

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