2,3-Butanediol diester derivatives, process for producing the sa

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424314, 260410, 2604109R, 260413, A01N 3702, A01N 3706, A01K 3123

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active

044697040

ABSTRACT:
The specification describes as antiulcer drug containing as an active ingredient a 2,3-butanediol diester derivative represented by the formula (I): ##STR1## where R.sub.A may for example be a saturated or unsaturated alkyl or phenyl styryl group and R.sub.B may for example be a saturated or unsaturated alkyl, phenyl, phenylalkyl, phenylpropenyl or phenoxyalkyl group. These groups may optionally be substituted. Many of 2,3-butanediol diester derivatives embraced by the formula (I) are novel. Also described are a novel process for preparing such novel 2,3-butanediol diester derivatives. The 2,3-butandiol diester derivatives of the formula (I) has an action to depress strongly the growth of peptic ulcer and has a very low toxicity.

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patent: 4272548 (1981-06-01), Gatzen et al.
Shanzer, Tetrahedron Letters, vol. 21, pp. 221-222, (1980).

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